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Uptodate. Com ©2012 uptodate® print | back full text close please select the full text article you wish to view: print medline ® abstract for reference 58 of 'local treatment for primary soft tissue sarcoma of the extremities and chest wall' 58 pubmed ti role of sentinel lymph node biopsy in the staging of synovial, epithelioid, and clear cell sarcomas. Au maduekwe un, hornicek fj, springfield ds, raskin ka, harmon dc, choy e, rosenberg ae, nielsen gp, delaney tf, chen yl, ott mj, yoon ss so ann surg oncol.
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background: soft tissue sarcomas generally have a=5% risk of lymph node metastasis, but synovial, epithelioid, and clear cell subtypes reportedly have a much higher risk. viagra lilly original The utility of sentinel lymph node biopsy (slnb) for patients with these sarcoma subtypes is unknown. viagra safe older men Methods: 29 patients with nonmetastatic synovial, epithelioid, and clear cell sarcomas who underwent slnb were examined.
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Results: median age was 35 years (range 11-73 years), and 69% were male.
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Tumors were located in the lower extremity in 17 patients and the upper extremity in 12.
The histological subtypes were synovial sarcoma in 16 patients, epithelioid sarcoma in 10, and clear cell sarcoma in 3.
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All patients had a staging chest computed tomography (ct) scan, none of which were suspicious, and 20 patients had staging positron emission tomography (pet) scans (16 negative, 3 indeterminate, and 1 suspicious). viagra pills used All patients had resection of their primary tumor.
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At least one sentinel node was found in 28 patients (97%), and the median number of sentinel nodes identified was 2 (range 1-4).
One patient had a positive sentinel node on routine hematoxylin and eosin (h&e) staining and developed lung metastases. Two patients had positive sentinel nodes following immunohistochemical staining, and both remain disease free despite not undergoing completion lymphadenectomy. One patient developed a lymph node metastasis after a negative slnb. buy viagra cheap canada Conclusion: for patients with these sarcoma subtypes without radiological evidence of nodal or distant metastases, the incidence of occult lymph node metastasis is relatively low. Determining utility of slnb may require a multicenter trial. free viagra trial Ad division of surgical oncology, department of surgery, massachusetts general hospital, boston, ma, usa.
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Pmid 19259743 .
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